4v8z

Electron Microscopy
6.6Å resolution

Cryo-EM reconstruction of the 80S-eIF5B-Met-itRNAMet Eukaryotic Translation Initiation Complex

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero 85-mer (preferred)
Entry contents:
79 distinct polypeptide molecules
6 distinct RNA molecules
Macromolecules (85 distinct):
40S ribosomal protein S26-A Chain: A0
Molecule details ›
Chain: A0
Length: 119 amino acids
Theoretical weight: 13.54 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P39938 (Residues: 1-119; Coverage: 100%)
Gene names: G1355, RPS26, RPS26A, YGL189C
Sequence domains: Ribosomal protein S26e
40S ribosomal protein S27-A Chain: A1
Molecule details ›
Chain: A1
Length: 82 amino acids
Theoretical weight: 8.89 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P35997 (Residues: 1-82; Coverage: 100%)
Gene names: RPS27A, YKL156W
Sequence domains: Ribosomal protein S27
40S ribosomal protein S28-A Chain: A2
Molecule details ›
Chain: A2
Length: 67 amino acids
Theoretical weight: 7.61 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: Q3E7X9 (Residues: 1-67; Coverage: 100%)
Gene names: O3600, RPS28A, RPS33, RPS33A, YOR167C
Sequence domains: Ribosomal protein S28e
40S ribosomal protein S29-A Chain: A3
Molecule details ›
Chain: A3
Length: 56 amino acids
Theoretical weight: 6.68 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P41057 (Residues: 1-56; Coverage: 100%)
Gene names: L8084.11, RPS29A, RPS36A, YLR388W, YS29A
Sequence domains: Ribosomal protein S14p/S29e
40S ribosomal protein S30-A Chain: A4
Molecule details ›
Chain: A4
Length: 63 amino acids
Theoretical weight: 7.14 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P0CX33 (Residues: 1-63; Coverage: 100%)
Gene names: L8003.23, RPS30A, YLR287BC, YLR287C-A
Sequence domains: Ribosomal protein S30
Ubiquitin-40S ribosomal protein S31 Chain: A5
Molecule details ›
Chain: A5
Length: 152 amino acids
Theoretical weight: 16.56 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P05759 (Residues: 1-152; Coverage: 100%)
Gene names: L9470.14, RPS31, RPS37, UBI3, YLR167W
Sequence domains:
Guanine nucleotide-binding protein subunit beta-like protein Chain: A6
Molecule details ›
Chain: A6
Length: 319 amino acids
Theoretical weight: 34.84 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P38011 (Residues: 1-319; Coverage: 100%)
Gene names: ASC1, CPC2, YM9718.15C, YMR116C
Sequence domains: WD domain, G-beta repeat
Suppressor protein STM1 Chain: A7
Molecule details ›
Chain: A7
Length: 273 amino acids
Theoretical weight: 29.05 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P39015 (Residues: 1-273; Coverage: 100%)
Gene names: L9634.1, MPT4, STM1, STO1, YLR150W
Sequence domains: Stm1
40S ribosomal protein S0-A Chain: AA
Molecule details ›
Chain: AA
Length: 252 amino acids
Theoretical weight: 28.05 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P32905 (Residues: 1-252; Coverage: 100%)
Gene names: NAB1, NAB1A, RPS0A, YGR214W, YST1
Sequence domains: Ribosomal protein S2
40S ribosomal protein S1-A Chain: AB
Molecule details ›
Chain: AB
Length: 255 amino acids
Theoretical weight: 28.8 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P33442 (Residues: 1-255; Coverage: 100%)
Gene names: L9753.9, PLC1, RPS10A, RPS1A, YLR441C
Sequence domains: Ribosomal S3Ae family
40S ribosomal protein S2 Chain: AC
Molecule details ›
Chain: AC
Length: 254 amino acids
Theoretical weight: 27.49 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P25443 (Residues: 1-254; Coverage: 100%)
Gene names: G2893, RPS2, RPS4, SUP38, SUP44, YGL123W
Sequence domains:
40S ribosomal protein S3 Chain: AD
Molecule details ›
Chain: AD
Length: 240 amino acids
Theoretical weight: 26.54 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P05750 (Residues: 1-240; Coverage: 100%)
Gene names: N1653, RPS3, SUF14, YNL178W
Sequence domains:
40S ribosomal protein S4-A Chain: AE
Molecule details ›
Chain: AE
Length: 261 amino acids
Theoretical weight: 29.47 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P0CX35 (Residues: 1-261; Coverage: 100%)
Gene names: J2186, RPS4A, RPS7B, YJR145C
Sequence domains:
40S ribosomal protein S5 Chain: AF
Molecule details ›
Chain: AF
Length: 225 amino acids
Theoretical weight: 25.07 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P26783 (Residues: 1-225; Coverage: 100%)
Gene names: J2045, RPS2, RPS5, YJR123W
Sequence domains: Ribosomal protein S7p/S5e
40S ribosomal protein S6-A Chain: AG
Molecule details ›
Chain: AG
Length: 236 amino acids
Theoretical weight: 27.05 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P0CX37 (Residues: 1-236; Coverage: 100%)
Gene names: LPG18C, RPS101, RPS10B, RPS6A, YPL090C
Sequence domains: Ribosomal protein S6e
40S ribosomal protein S7-A Chain: AH
Molecule details ›
Chain: AH
Length: 190 amino acids
Theoretical weight: 21.66 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P26786 (Residues: 1-190; Coverage: 100%)
Gene names: RPS30, RPS7A, YOR096W, YOR3177W
Sequence domains: Ribosomal protein S7e
40S ribosomal protein S8-A Chain: AI
Molecule details ›
Chain: AI
Length: 200 amino acids
Theoretical weight: 22.54 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P0CX39 (Residues: 1-200; Coverage: 100%)
Gene names: RPS14A, RPS8A, YBL06.05, YBL0613, YBL072C
Sequence domains: Ribosomal protein S8e
40S ribosomal protein S9-A Chain: AJ
Molecule details ›
Chain: AJ
Length: 197 amino acids
Theoretical weight: 22.49 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: O13516 (Residues: 1-197; Coverage: 100%)
Gene names: RPS13A, RPS9A, YPL081W, YS11A
Sequence domains: S4 domain
40S ribosomal protein S10-A Chain: AK
Molecule details ›
Chain: AK
Length: 105 amino acids
Theoretical weight: 12.76 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: Q08745 (Residues: 1-105; Coverage: 100%)
Gene names: RPS10A, YOR293W
Sequence domains: Plectin/S10 domain
40S ribosomal protein S11-A Chain: AL
Molecule details ›
Chain: AL
Length: 156 amino acids
Theoretical weight: 17.79 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P0CX47 (Residues: 1-156; Coverage: 100%)
Gene names: RPS11A, RPS18A, YD9813.03, YDR025W
Sequence domains:
40S ribosomal protein S12 Chain: AM
Molecule details ›
Chain: AM
Length: 143 amino acids
Theoretical weight: 15.49 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P48589 (Residues: 1-143; Coverage: 100%)
Gene names: RPS12, YOR369C
Sequence domains: Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
40S ribosomal protein S13 Chain: AN
Molecule details ›
Chain: AN
Length: 151 amino acids
Theoretical weight: 17.06 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P05756 (Residues: 1-151; Coverage: 100%)
Gene names: D4252, RPS13, RPS13C, YD9609.18, YDR064W
Sequence domains:
40S ribosomal protein S14-A Chain: AO
Molecule details ›
Chain: AO
Length: 137 amino acids
Theoretical weight: 14.56 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P06367 (Residues: 1-137; Coverage: 100%)
Gene names: CRY1, RPL59, RPS14A, YCR031C, YCR31C
Sequence domains: Ribosomal protein S11
40S ribosomal protein S15 Chain: AP
Molecule details ›
Chain: AP
Length: 142 amino acids
Theoretical weight: 16.03 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: Q01855 (Residues: 1-142; Coverage: 100%)
Gene names: RPS15, RPS21, YOL040C
Sequence domains: Ribosomal protein S19
40S ribosomal protein S16-A Chain: AQ
Molecule details ›
Chain: AQ
Length: 143 amino acids
Theoretical weight: 15.88 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P0CX51 (Residues: 1-143; Coverage: 100%)
Gene names: RP61R, RPS16A, YM9375.12, YMR143W
Sequence domains: Ribosomal protein S9/S16
40S ribosomal protein S17-A Chain: AR
Molecule details ›
Chain: AR
Length: 136 amino acids
Theoretical weight: 15.82 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P02407 (Residues: 1-136; Coverage: 100%)
Gene names: RP51A, RPS17A, YML024W
Sequence domains: Ribosomal S17
40S ribosomal protein S18-A Chain: AS
Molecule details ›
Chain: AS
Length: 146 amino acids
Theoretical weight: 17.07 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P0CX55 (Residues: 1-146; Coverage: 100%)
Gene names: D9461.35, RPS18A, YDR450W
Sequence domains: Ribosomal protein S13/S18
40S ribosomal protein S19-A Chain: AT
Molecule details ›
Chain: AT
Length: 144 amino acids
Theoretical weight: 15.94 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P07280 (Residues: 1-144; Coverage: 100%)
Gene names: RP55A, RPS16AA, RPS19A, YOL121C
Sequence domains: Ribosomal protein S19e
40S ribosomal protein S20 Chain: AU
Molecule details ›
Chain: AU
Length: 121 amino acids
Theoretical weight: 13.93 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P38701 (Residues: 1-121; Coverage: 100%)
Gene names: RPS20, URP2, YHL015W
Sequence domains: Ribosomal protein S10p/S20e
40S ribosomal protein S21-A Chain: AV
Molecule details ›
Chain: AV
Length: 87 amino acids
Theoretical weight: 9.76 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P0C0V8 (Residues: 1-87; Coverage: 100%)
Gene names: RPS21A, RPS25, RPS25A, RPS26A, YKR057W
Sequence domains: Ribosomal protein S21e
40S ribosomal protein S22-A Chain: AW
Molecule details ›
Chain: AW
Length: 130 amino acids
Theoretical weight: 14.65 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P0C0W1 (Residues: 1-130; Coverage: 100%)
Gene names: J0355, RPS22A, RPS24, RPS24A, YJL190C
Sequence domains: Ribosomal protein S8
40S ribosomal protein S23-A Chain: AX
Molecule details ›
Chain: AX
Length: 145 amino acids
Theoretical weight: 16.07 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P0CX29 (Residues: 1-145; Coverage: 100%)
Gene names: G6178, RPS23A, RPS28A, YGR118W
Sequence domains: Ribosomal protein S12/S23
40S ribosomal protein S24-A Chain: AY
Molecule details ›
Chain: AY
Length: 135 amino acids
Theoretical weight: 15.36 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P0CX31 (Residues: 1-135; Coverage: 100%)
Gene names: RPS24A, RPS24EA, YER074W
Sequence domains: Ribosomal protein S24e
40S ribosomal protein S25-A Chain: AZ
Molecule details ›
Chain: AZ
Length: 108 amino acids
Theoretical weight: 12.07 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: Q3E792 (Residues: 1-108; Coverage: 100%)
Gene names: RPS25A, RPS31A, YGR027C
Sequence domains: S25 ribosomal protein
60S ribosomal protein L2-B Chain: BA
Molecule details ›
Chain: BA
Length: 253 amino acids
Theoretical weight: 27.33 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P0CX46 (Residues: 2-254; Coverage: 100%)
Gene names: RPL2B, RPL5A, YIL018W
Sequence domains:
60S ribosomal protein L3 Chain: BB
Molecule details ›
Chain: BB
Length: 386 amino acids
Theoretical weight: 43.72 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P14126 (Residues: 2-387; Coverage: 100%)
Gene names: MAK8, RPL3, TCM1, YOR063W, YOR29-14
60S ribosomal protein L4-A Chain: BC
Molecule details ›
Chain: BC
Length: 361 amino acids
Theoretical weight: 39.03 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P10664 (Residues: 2-362; Coverage: 100%)
Gene names: RPL2, RPL2A, RPL4A, YBR0315, YBR031W
Sequence domains:
60S ribosomal protein L5 Chain: BD
Molecule details ›
Chain: BD
Length: 296 amino acids
Theoretical weight: 33.63 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P26321 (Residues: 2-297; Coverage: 100%)
Gene names: LPI14W, RPL1, RPL1A, RPL5, YPL131W
Sequence domains:
60S ribosomal protein L6-A Chain: BE
Molecule details ›
Chain: BE
Length: 175 amino acids
Theoretical weight: 19.87 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: Q02326 (Residues: 2-176; Coverage: 99%)
Gene names: RPL17A, RPL6A, YL16A, YML073C
Sequence domains: Ribosomal protein L6e
60S ribosomal protein L7-A Chain: BF
Molecule details ›
Chain: BF
Length: 243 amino acids
Theoretical weight: 27.56 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P05737 (Residues: 2-244; Coverage: 100%)
Gene names: RPL6A, RPL7A, RPL8A, YGL076C, YL8A
Sequence domains:
60S ribosomal protein L8-A Chain: BG
Molecule details ›
Chain: BG
Length: 255 amino acids
Theoretical weight: 28.04 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P17076 (Residues: 2-256; Coverage: 100%)
Gene names: MAK7, RPL4A, RPL8A, YHL033C
Sequence domains: Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
60S ribosomal protein L9-A Chain: BH
Molecule details ›
Chain: BH
Length: 191 amino acids
Theoretical weight: 21.61 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P05738 (Residues: 1-191; Coverage: 100%)
Gene names: RPL8A, RPL9, RPL9A, YGL147C
Sequence domains: Ribosomal protein L6
60S ribosomal protein L10 Chain: BI
Molecule details ›
Chain: BI
Length: 220 amino acids
Theoretical weight: 25.28 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P41805 (Residues: 2-221; Coverage: 100%)
Gene names: GRC5, QSR1, RPL10, YLR075W
Sequence domains: Ribosomal protein L16p/L10e
60S ribosomal protein L11-A Chain: BJ
Molecule details ›
Chain: BJ
Length: 173 amino acids
Theoretical weight: 19.62 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P0C0W9 (Residues: 2-174; Coverage: 99%)
Gene names: P8283.14, RP39A, RPL11A, RPL16A, YPR102C
Sequence domains:
60S RIBOSOMAL PROTEIN L11-A Chain: BK
Molecule details ›
Chain: BK
Length: 174 amino acids
Theoretical weight: 14.83 KDa
Source organism: Saccharomyces cerevisiae
60S ribosomal protein L13-A Chain: BL
Molecule details ›
Chain: BL
Length: 198 amino acids
Theoretical weight: 22.47 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: Q12690 (Residues: 2-199; Coverage: 100%)
Gene names: RPL13A, YDL082W
Sequence domains: Ribosomal protein L13e
60S ribosomal protein L14-B Chain: BM
Molecule details ›
Chain: BM
Length: 137 amino acids
Theoretical weight: 15.06 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P38754 (Residues: 2-138; Coverage: 99%)
Gene names: RPL14B, YHL001W
Sequence domains: Ribosomal protein L14
60S ribosomal protein L15-A Chain: BN
Molecule details ›
Chain: BN
Length: 203 amino acids
Theoretical weight: 24.35 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P05748 (Residues: 2-204; Coverage: 100%)
Gene names: RPL10A, RPL13A, RPL15A, YL10A, YLR029C
Sequence domains: Ribosomal L15
60S ribosomal protein L16-A Chain: BO
Molecule details ›
Chain: BO
Length: 198 amino acids
Theoretical weight: 22.12 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P26784 (Residues: 2-199; Coverage: 100%)
Gene names: RPL13, RPL16A, RPL21A, YIL133C
Sequence domains: Ribosomal protein L13
60S ribosomal protein L17-A Chain: BP
Molecule details ›
Chain: BP
Length: 183 amino acids
Theoretical weight: 20.46 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P05740 (Residues: 2-184; Coverage: 100%)
Gene names: RPL17, RPL17A, RPL20A, YKL180W
Sequence domains: Ribosomal protein L22p/L17e
60S ribosomal protein L18-A Chain: BQ
Molecule details ›
Chain: BQ
Length: 185 amino acids
Theoretical weight: 20.48 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P0CX49 (Residues: 2-186; Coverage: 100%)
Gene names: RP28A, RPL18A, YOL120C
Sequence domains: Ribosomal protein 60S L18 and 50S L18e
60S ribosomal protein L19-B Chain: BR
Molecule details ›
Chain: BR
Length: 188 amino acids
Theoretical weight: 21.63 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P0CX83 (Residues: 2-189; Coverage: 100%)
Gene names: RPL19B, RPL23B, YBL027W, YBL0424, YL14B
Sequence domains: Ribosomal protein L19e
60S ribosomal protein L20-B Chain: BS
Molecule details ›
Chain: BS
Length: 172 amino acids
Theoretical weight: 20.48 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P0CX24 (Residues: 1-172; Coverage: 100%)
Gene names: O6116, RPL18A1, RPL18B, RPL20B, YOR312C
Sequence domains: Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A
60S ribosomal protein L21-A Chain: BT
Molecule details ›
Chain: BT
Length: 159 amino acids
Theoretical weight: 18.15 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: Q02753 (Residues: 2-160; Coverage: 99%)
Gene names: RPL21A, URP1, YBR1401, YBR191W
60S ribosomal protein L22-A Chain: BU
Molecule details ›
Chain: BU
Length: 120 amino acids
Theoretical weight: 13.58 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P05749 (Residues: 2-121; Coverage: 99%)
Gene names: L2168, RPL22A, YLR061W
Sequence domains: Ribosomal L22e protein family
60S ribosomal protein L23-A Chain: BV
Molecule details ›
Chain: BV
Length: 136 amino acids
Theoretical weight: 14.36 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P0CX41 (Residues: 2-137; Coverage: 99%)
Gene names: RPL17A, RPL17AA, RPL23A, YBL0713, YBL087C
Sequence domains: Ribosomal protein L14p/L23e
60S ribosomal protein L24-A Chain: BW
Molecule details ›
Chain: BW
Length: 155 amino acids
Theoretical weight: 17.66 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P04449 (Residues: 1-155; Coverage: 100%)
Gene names: RP29, RPL24A, RPL30A, YGL031C
Sequence domains: Ribosomal protein L24e
60S ribosomal protein L25 Chain: BX
Molecule details ›
Chain: BX
Length: 141 amino acids
Theoretical weight: 15.66 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P04456 (Residues: 2-142; Coverage: 99%)
Gene names: RPL25, YOL127W
Sequence domains:
60S ribosomal protein L26-A Chain: BY
Molecule details ›
Chain: BY
Length: 126 amino acids
Theoretical weight: 14.13 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P05743 (Residues: 2-127; Coverage: 99%)
Gene names: L8300.4, RPL26, RPL26A, RPL33A, YLR344W
Sequence domains:
60S ribosomal protein L27-A Chain: BZ
Molecule details ›
Chain: BZ
Length: 135 amino acids
Theoretical weight: 15.44 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P0C2H6 (Residues: 2-136; Coverage: 99%)
Gene names: RPL27, RPL27A, YHR010W
Sequence domains: Ribosomal L27e protein family
60S ribosomal protein L28 Chain: Ba
Molecule details ›
Chain: Ba
Length: 148 amino acids
Theoretical weight: 16.63 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P02406 (Residues: 2-149; Coverage: 99%)
Gene names: CYH2, RPL28, YGL103W
Sequence domains: Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A
60S ribosomal protein L29 Chain: Bb
Molecule details ›
Chain: Bb
Length: 58 amino acids
Theoretical weight: 6.56 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P05747 (Residues: 2-59; Coverage: 98%)
Gene names: RPL29, YFR032BW, YFR032C-A, YL43
Sequence domains: Ribosomal L29e protein family
60S ribosomal protein L30 Chain: Bc
Molecule details ›
Chain: Bc
Length: 104 amino acids
Theoretical weight: 11.3 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P14120 (Residues: 2-105; Coverage: 99%)
Gene names: RPL30, RPL32, YGL030W
Sequence domains: Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
60S ribosomal protein L31-A Chain: Bd
Molecule details ›
Chain: Bd
Length: 112 amino acids
Theoretical weight: 12.85 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P0C2H8 (Residues: 2-113; Coverage: 99%)
Gene names: D2478, RPL31A, RPL34, RPL34A, YDL075W
Sequence domains: Ribosomal protein L31e
60S ribosomal protein L32 Chain: Be
Molecule details ›
Chain: Be
Length: 129 amino acids
Theoretical weight: 14.68 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P38061 (Residues: 2-130; Coverage: 99%)
Gene names: RPL32, YBL0838, YBL092W
Sequence domains: Ribosomal protein L32
60S ribosomal protein L33-A Chain: Bf
Molecule details ›
Chain: Bf
Length: 106 amino acids
Theoretical weight: 12.05 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P05744 (Residues: 2-107; Coverage: 99%)
Gene names: LPI4W, P2625, RPL33A, RPL37A, YPL143W
Sequence domains: Ribosomal protein L35Ae
60S ribosomal protein L34-A Chain: Bg
Molecule details ›
Chain: Bg
Length: 120 amino acids
Theoretical weight: 13.54 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P87262 (Residues: 2-121; Coverage: 99%)
Gene names: RPL34A, YER056BC, YER056C-A
60S ribosomal protein L35-B Chain: Bh
Molecule details ›
Chain: Bh
Length: 119 amino acids
Theoretical weight: 13.81 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P0CX85 (Residues: 2-120; Coverage: 99%)
Gene names: D2170, RPL35B, SOS2, YDL136W
Sequence domains: Ribosomal L29 protein
60S ribosomal protein L36-A Chain: Bi
Molecule details ›
Chain: Bi
Length: 99 amino acids
Theoretical weight: 11.02 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P05745 (Residues: 2-100; Coverage: 99%)
Gene names: RPL36A, RPL39A, YM9646.06, YMR194W
Sequence domains: Ribosomal protein L36e
60S ribosomal protein L37-A Chain: Bj
Molecule details ›
Chain: Bj
Length: 87 amino acids
Theoretical weight: 9.75 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P49166 (Residues: 2-88; Coverage: 99%)
Gene names: L9470.6, RPL35A, RPL37A, YLR185W
Sequence domains: Ribosomal protein L37e
60S ribosomal protein L38 Chain: Bk
Molecule details ›
Chain: Bk
Length: 77 amino acids
Theoretical weight: 8.71 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P49167 (Residues: 2-78; Coverage: 99%)
Gene names: L8543.2, RPL38, YLR325C
Sequence domains: Ribosomal L38e protein family
60S ribosomal protein L39 Chain: Bl
Molecule details ›
Chain: Bl
Length: 50 amino acids
Theoretical weight: 6.23 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P04650 (Residues: 2-51; Coverage: 98%)
Gene names: J0360, RPL39, RPL46, SPB2, YJL189W
Sequence domains: Ribosomal L39 protein
Ubiquitin-60S ribosomal protein L40 Chain: Bm
Molecule details ›
Chain: Bm
Length: 128 amino acids
Theoretical weight: 14.58 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P0CH08 (Residues: 1-128; Coverage: 100%)
Gene names: RPL40A, UBI1, YIL148W
Sequence domains:
60S ribosomal protein L41-B Chain: Bn
Molecule details ›
Chain: Bn
Length: 25 amino acids
Theoretical weight: 3.35 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P0CX87 (Residues: 1-25; Coverage: 100%)
Gene names: RPL41B, RPL47B, YDL133BC, YDL133C-A, YL41B
Sequence domains: Ribosomal protein L41
60S ribosomal protein L42-A Chain: Bo
Molecule details ›
Chain: Bo
Length: 105 amino acids
Theoretical weight: 12.12 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P0CX27 (Residues: 2-106; Coverage: 99%)
Gene names: N1722, RPL41A, RPL42A, SCL41A, YNL162W
Sequence domains: Ribosomal protein L44
60S acidic ribosomal protein P0 Chain: Bq
Molecule details ›
Chain: Bq
Length: 312 amino acids
Theoretical weight: 33.75 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P05317 (Residues: 1-312; Coverage: 100%)
Gene names: L10E, L8300.8, RPA0, RPL10E, RPLA0, RPP0, YLR340W
Sequence domains:
60S ACIDIC RIBOSOMAL PROTEIN P1 Chain: Br
Molecule details ›
Chain: Br
Length: 47 amino acids
Theoretical weight: 4.02 KDa
Source organism: Saccharomyces cerevisiae
60S ACIDIC RIBOSOMAL PROTEIN P2 Chain: Bs
Molecule details ›
Chain: Bs
Length: 46 amino acids
Theoretical weight: 3.93 KDa
Source organism: Saccharomyces cerevisiae
Eukaryotic translation initiation factor 5B; Probable translation initiation factor IF-2 Chain: CV
Molecule details ›
Chain: CV
Length: 586 amino acids
Theoretical weight: 65.19 KDa
Source organisms: Expression system: Escherichia coli
UniProt:
  • Canonical: O26359 (Residues: 351-586; Coverage: 40%)
  • Canonical: P39730 (Residues: 401-739; Coverage: 34%)
Gene names: FUN12, MTH_259, YAL035W, infB
Sequence domains:
18S Ribosomal RNA Chain: B2
Molecule details ›
Chain: B2
Length: 1800 nucleotides
Theoretical weight: 577.94 KDa
Sequence domains: Eukaryotic small subunit ribosomal RNA
25S ribosomal RNA Chain: B5
Molecule details ›
Chain: B5
Length: 3396 nucleotides
Theoretical weight: 1097.49 KDa
Sequence domains: Eukaryotic large subunit ribosomal RNA
5S ribosomal RNA Chain: B7
Molecule details ›
Chain: B7
Length: 121 nucleotides
Theoretical weight: 38.95 KDa
Sequence domains: 5S ribosomal RNA
5.8S ribosomal RNA Chain: B8
Molecule details ›
Chain: B8
Length: 158 nucleotides
Theoretical weight: 50.68 KDa
Sequence domains: 5.8S ribosomal RNA
EUKARYOTIC RIBOSOMAL PI TRNA Chain: CW
Molecule details ›
Chain: CW
Length: 76 nucleotides
Theoretical weight: 24.42 KDa
Sequence domains: tRNA
5'-R(*AP*UP*GP)-3' Chain: CX
Molecule details ›
Chain: CX
Length: 3 nucleotides
Theoretical weight: 936 Da

Ligands and Environments

1 modified residue:

Experiments and Validation Details

Entry percentile scores
Resolution: 6.6Å
Relevant EMDB volumes: EMD-2422
Expression system: Escherichia coli