4v3c

X-ray diffraction
1.84Å resolution

The structure of alpha2,3-sialyltransferase variant 2 from Pasteurella dagmatis in complex with the donor product CMP

Released:
Source organism: Pasteurella dagmatis
Entry authors: Pavkov-Keller T, Schmoelzer K, Czabany T, Luley-Goedl C, Ribitsch D, Schwab H, Nidetzky B, Gruber K

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Sialyltransferase Chain: A
Molecule details ›
Chain: A
Length: 388 amino acids
Theoretical weight: 45.64 KDa
Source organism: Pasteurella dagmatis
Expression system: Escherichia coli
UniProt:
  • Canonical: K9UUI6 (Residues: 2-385; Coverage: 100%)
Sequence domains: Sialyltransferase PMO188
Structure domains:

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID29
Spacegroup: P65
Unit cell:
a: 111.75Å b: 111.75Å c: 65.19Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.175 0.173 0.218
Expression system: Escherichia coli