Function and Biology

Conserved mechanisms of microtubule-stimulated ADP release, ATP binding, and force generation in transport kinesins

Source organisms:
Biochemical function: GTP binding
Biological process: microtubule cytoskeleton organization
Cellular component: microtubule

Sequence families

Pfam Protein families (Pfam)
PF00091
Domain description: Tubulin/FtsZ family, GTPase domain
Occurring in:
  1. Tubulin alpha-1B chain
  2. Tubulin beta-2B chain
1 copy of Pfam domain PF00091 (Tubulin/FtsZ family, GTPase domain) in Tubulin alpha-1B chain in PDB 4uxt.
2 copies of Pfam domain PF00091 (Tubulin/FtsZ family, GTPase domain) in Tubulin beta-2B chain in PDB 4uxt.

PF03953
Domain description: Tubulin C-terminal domain
Occurring in:
  1. Tubulin alpha-1B chain
  2. Tubulin beta-2B chain
1 copy of Pfam domain PF03953 (Tubulin C-terminal domain) in Tubulin alpha-1B chain in PDB 4uxt.
2 copies of Pfam domain PF03953 (Tubulin C-terminal domain) in Tubulin beta-2B chain in PDB 4uxt.

PF00225
Domain description: Kinesin motor domain
Occurring in:
  1. Kinesin heavy chain isoform 5A
1 copy of Pfam domain PF00225 (Kinesin motor domain) in Kinesin heavy chain isoform 5A in PDB 4uxt.

InterPro InterPro annotations
IPR000217
Domain description: Tubulin
Occurring in:
  1. Tubulin alpha-1B chain
  2. Tubulin beta-2B chain
IPR002452
Domain description: Alpha tubulin
Occurring in:
  1. Tubulin alpha-1B chain
IPR002453
Domain description: Beta tubulin
Occurring in:
  1. Tubulin beta-2B chain
IPR001752
Domain description: Kinesin motor domain
Occurring in:
  1. Kinesin heavy chain isoform 5A
IPR003008
Domain description: Tubulin/FtsZ, GTPase domain
Occurring in:
  1. Tubulin alpha-1B chain
  2. Tubulin beta-2B chain
IPR036525
Domain description: Tubulin/FtsZ, GTPase domain superfamily
Occurring in:
  1. Tubulin alpha-1B chain
  2. Tubulin beta-2B chain
IPR018316
Domain description: Tubulin/FtsZ, 2-layer sandwich domain
Occurring in:
  1. Tubulin alpha-1B chain
  2. Tubulin beta-2B chain
IPR037103
Domain description: Tubulin/FtsZ, C-terminal domain superfamily
Occurring in:
  1. Tubulin alpha-1B chain
  2. Tubulin beta-2B chain
IPR023123
Domain description: Tubulin, C-terminal
Occurring in:
  1. Tubulin alpha-1B chain
  2. Tubulin beta-2B chain
IPR008280
Domain description: Tubulin/FtsZ, C-terminal
Occurring in:
  1. Tubulin alpha-1B chain
  2. Tubulin beta-2B chain
IPR027640
Domain description: Kinesin-like protein
Occurring in:
  1. Kinesin heavy chain isoform 5A
IPR027417
Domain description: P-loop containing nucleoside triphosphate hydrolase
Occurring in:
  1. Kinesin heavy chain isoform 5A
IPR036961
Domain description: Kinesin motor domain superfamily
Occurring in:
  1. Kinesin heavy chain isoform 5A