X-ray diffraction
1.66Å resolution

VIM-26-PEG. Leu224 in VIM-26 from Klebsiella pneumoniae has implications for drug binding.


Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Lactamase_B domain-containing protein Chain: B
Molecule details ›
Chain: B
Length: 266 amino acids
Theoretical weight: 28.07 KDa
Source organism: Klebsiella pneumoniae
Expression system: Escherichia coli BL21(DE3)
  • Canonical: E5BDC6 (Residues: 1-266; Coverage: 100%)
Gene name: blaVIM-26
Sequence domains: Metallo-beta-lactamase superfamily
Structure domains: Ribonuclease Z/Hydroxyacylglutathione hydrolase-like

Ligands and Environments

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: BESSY BEAMLINE 14.1
Spacegroup: P21
Unit cell:
a: 39.759Å b: 68.172Å c: 40.406Å
α: 90° β: 92.56° γ: 90°
R R work R free
0.158 0.156 0.2
Expression system: Escherichia coli BL21(DE3)