X-ray diffraction
1.3Å resolution

BROMODOMAIN OF HUMAN BRD9 WITH 7-(3,4-dimethoxyphenyl)-2-(4- methanesulfonylpiperazine-1-carbonyl)-5-methyl-4H,5H-thieno-3,2-c- pyridin-4-one


Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Bromodomain-containing protein 9 Chain: A
Molecule details ›
Chain: A
Length: 106 amino acids
Theoretical weight: 12.23 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: Q9H8M2 (Residues: 134-238; Coverage: 18%)
Gene names: BRD9, UNQ3040/PRO9856
Sequence domains: Bromodomain
Structure domains: Bromodomain-like

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I02
Spacegroup: P1
Unit cell:
a: 24.7Å b: 34.11Å c: 39.68Å
α: 70.26° β: 73.8° γ: 74.24°
R R work R free
0.153 0.152 0.173
Expression system: Escherichia coli