› 4ueg

X-ray diffraction
1.93Å resolution

Crystal structure of human glycogenin-2 catalytic domain

Released:
DOI: 10.2210/pdb4ueg/pdb
PDB entry 4ueg coloured by chain, front view.
PDB entry 4ueg coloured by chain, side view.
PDB entry 4ueg coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Fairhead M, Strain-Damerell C, Krojer T, Froese DS, Kopec J, Nowak R, Burgess-Brown N, von Delft F, Arrowsmith C, Edwards A, Bountra C, Yue WW

Function and Biology Details

Reaction catalysed: 
UDP-alpha-D-glucose + glycogenin = UDP + alpha-D-glucosylglycogenin
Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-127492 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Glycogenin-2 Chains: A, B
Molecule details ›
Chains: A, B
Length: 288 amino acids
Theoretical weight: 33.1 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: O15488 (Residues: 35-300; Coverage: 53%)
Gene name: GYG2
Sequence domains: Glycosyl transferase family 8
Structure domains: Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A

Ligands and Environments

1 bound ligand:
Ligand MG 2 x MG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I03
Spacegroup: C2
Unit cell:
a: 127.113Å b: 80.541Å c: 73.683Å
α: 90° β: 118.74° γ: 90°
R-values:
R R work R free
0.188 0.187 0.224
Expression system: Escherichia coli BL21(DE3)

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