› 4uby

X-ray diffraction
1Å resolution

Crystal structure of a polymorphic beta1 peptide

Released:
DOI: 10.2210/pdb4uby/pdb
PDB entry 4uby coloured by chain, front view.
PDB entry 4uby coloured by chain, side view.
PDB entry 4uby coloured by chain, top view.
Source organism: synthetic construct
Primary publication:
Crystal Structures of Polymorphic Prion Protein β1 Peptides Reveal Variable Steric Zipper Conformations.
Yu L, Lee SJ, Yee VC
Biochemistry 54 3640-8 (2015)
PMID: 25978088

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo hexadecamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-165212 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
prion peptide Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 6 amino acids
Theoretical weight: 565 Da
Source organism: synthetic construct
Expression system: Not provided

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 23-ID-B
Spacegroup: P1
Unit cell:
a: 11.666Å b: 17.145Å c: 19.073Å
α: 79.76° β: 86.51° γ: 90.2°
R-values:
R R work R free
0.122 0.12 0.158
Expression system: Not provided

Quick links

Citations

1 review citation

Toward the Atomic Structure of PrPSc.
Rodriguez et al. (2017)
7 other articles

2 mentions without citation

Autonomous aggregation suppression by acidic residues explains why chaperones favour basic residues.
Houben et al. (2020)
1 more