X-ray diffraction
1.85Å resolution

Crystal structure of selenomethionine labeled SpNatD


Function and Biology Details

Reaction catalysed:
Acetyl-CoA + an N-terminal-L-seryl-[histone H2A] = an N-terminal-N(alpha)-acetyl-L-seryl-[histone H2A] + CoA
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
N-alpha-acetyltransferase 40 Chains: A, B
Molecule details ›
Chains: A, B
Length: 194 amino acids
Theoretical weight: 23.34 KDa
Source organism: Schizosaccharomyces pombe 972h-
Expression system: Escherichia coli
  • Canonical: Q9USH6 (Residues: 13-204; Coverage: 94%)
Gene names: SPCC825.04c, naa40
Sequence domains: Acetyltransferase (GNAT) family
Structure domains: Aminopeptidase

Ligands and Environments

Cofactor: Ligand COA 2 x COA
1 bound ligand:
1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X29A
Spacegroup: C2
Unit cell:
a: 114.701Å b: 42.629Å c: 85.417Å
α: 90° β: 98.68° γ: 90°
R R work R free
0.182 0.179 0.239
Expression system: Escherichia coli