4txq

X-ray diffraction
2.21Å resolution

Crystal structure of LIP5 N-terminal domain complexed with CHMP1B MIM

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Vacuolar protein sorting-associated protein VTA1 homolog Chains: A, B
Molecule details ›
Chains: A, B
Length: 163 amino acids
Theoretical weight: 18.79 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9NP79 (Residues: 1-162; Coverage: 53%)
Gene names: C6orf55, HSPC228, My012, VTA1
Sequence domains: Vta1 like
Structure domains: Vacuolar protein sorting-associated protein vta1
Charged multivesicular body protein 1b Chains: C, D
Molecule details ›
Chains: C, D
Length: 25 amino acids
Theoretical weight: 2.72 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q7LBR1 (Residues: 176-199; Coverage: 12%)
Gene names: C18orf2, CHMP1B

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 21-ID-D
Spacegroup: P212121
Unit cell:
a: 52.936Å b: 55.536Å c: 195.359Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.196 0.193 0.227
Expression system: Escherichia coli