4tw2

X-ray diffraction
2.89Å resolution

Crystal Structure of SCARB2 in Neural Condition (pH7.5)

Released:
Source organism: Homo sapiens

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (6 distinct):
Lysosome membrane protein 2 Chains: A, B
Molecule details ›
Chains: A, B
Length: 394 amino acids
Theoretical weight: 45.22 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q14108 (Residues: 37-430; Coverage: 82%)
Gene names: CD36L2, LIMP2, LIMPII, SCARB2

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer : NEW Components: NAG, BMA
Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer : NEW Components: NAG, BMA, MAN
1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL26B1
Spacegroup: P21
Unit cell:
a: 57.796Å b: 100.317Å c: 105.173Å
α: 90° β: 98.69° γ: 90°
R-values:
R R work R free
0.246 0.244 0.294
Expression system: Spodoptera frugiperda