4tw0

X-ray diffraction
3.65Å resolution

Crystal Structure of SCARB2 in Acidic Condition (pH4.8)

Released:
Source organism: Homo sapiens

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (5 distinct):
Lysosome membrane protein 2 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 393 amino acids
Theoretical weight: 45.1 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q14108 (Residues: 37-429; Coverage: 82%)
Gene names: CD36L2, LIMP2, LIMPII, SCARB2

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer : NEW Components: NAG, BMA
1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PHOTON FACTORY BEAMLINE BL-17A
Spacegroup: P21
Unit cell:
a: 103.99Å b: 99.636Å c: 125.853Å
α: 90° β: 90.02° γ: 90°
R-values:
R R work R free
0.252 0.249 0.304
Expression system: Spodoptera frugiperda