› › Structure analysis

Crystal structure of the hydrolase domain of 10-formyltetrahydrofolate dehydrogenase (wild-type) complex with 10-formyl-5,8-dideazafolate

X-ray diffraction
2.301Å resolution
PDB entry 4tt8 coloured by chain, front view.
PDB entry 4tt8 coloured by chain, side view.
PDB entry 4tt8 coloured by chain, top view.
Source organism: Danio rerio
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

Quick links

Assemblies

Assembly 1 (preferred)
Download    3D Visualisation
Assembly Name: 10-formyltetrahydrofolate dehydrogenase
hide full assembly name
Multimeric state: monomeric
Accessible surface area: 14487.61 Å2
Buried surface area: 289.68 Å2
Dissociation area: 144.84 Å2
Dissociation energy (ΔGdiss): -6.09 kcal/mol
Dissociation entropy (TΔSdiss): 2.85 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-122879

Macromolecules

10-formyltetrahydrofolate dehydrogenase
Chain: A
Length: 318 amino acids
Theoretical weight: 35.46 KDa
Source organism: Danio rerio
Expression system: Escherichia coli
UniProt:
  • Canonical: E3NZ06 (Residues: 1-311; Coverage: 34%)
Gene name: aldh1l1
Pfam:
InterPro:
CATH:
10-formyltetrahydrofolate dehydrogenase in PDB entry 4tt8, assembly 1, front view.
10-formyltetrahydrofolate dehydrogenase in PDB entry 4tt8, assembly 1, side view.
10-formyltetrahydrofolate dehydrogenase in PDB entry 4tt8, assembly 1, top view.
Molecule details ›

Search similar proteins

Quick links