4tt2

X-ray diffraction
2.5Å resolution

Crystal structure of ATAD2A bromodomain complexed with H4(1-20)K5Ac peptide

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
ATPase family AAA domain-containing protein 2 Chain: A
Molecule details ›
Chain: A
Length: 130 amino acids
Theoretical weight: 15.45 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q6PL18 (Residues: 981-1108; Coverage: 9%)
Gene names: ATAD2, L16, PRO2000
Sequence domains: Bromodomain
Structure domains: Bromodomain-like
Histone H4K5Ac Chain: P
Molecule details ›
Chain: P
Length: 6 amino acids
Theoretical weight: 604 Da
Source organism: Homo sapiens
Expression system: Not provided

Ligands and Environments

No bound ligands
1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.3.1
Spacegroup: P42212
Unit cell:
a: 77.55Å b: 77.55Å c: 62.44Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.224 0.22 0.267
Expression systems:
  • Escherichia coli BL21(DE3)
  • Not provided