› 4tss

X-ray diffraction
2.75Å resolution

TOXIC SHOCK SYNDROME TOXIN-1: TETRAGONAL P4(1)2(1)2 CRYSTAL FORM

Released:
DOI: 10.2210/pdb4tss/pdb
PDB entry 4tss coloured by chain, front view.
PDB entry 4tss coloured by chain, side view.
PDB entry 4tss coloured by chain, top view.
Source organism: Staphylococcus aureus
Primary publication:
Refined structures of three crystal forms of toxic shock syndrome toxin-1 and of a tetramutant with reduced activity.
Prasad GS, Radhakrishnan R, Mitchell DT, Earhart CA, Dinges MM, Cook WJ, Schlievert PM, Ohlendorf DH
Protein Sci 6 1220-7 (1997)
PMID: 9194182

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-139296 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Toxic shock syndrome toxin-1 Chain: A
Molecule details ›
Chain: A
Length: 194 amino acids
Theoretical weight: 22.1 KDa
Source organism: Staphylococcus aureus
UniProt:
  • Canonical: P06886 (Residues: 41-234; Coverage: 100%)
Gene name: tst
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand ZN 1 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RUH2R
Spacegroup: P41212
Unit cell:
a: 47.3Å b: 47.3Å c: 205.8Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.191 0.191 not available

Quick links

Citations

5 review citations

Exotoxins of Staphylococcus aureus.
Dinges et al. (2000)
4 more

1 mention without citation

A generic approach to evaluate how B-cell epitopes are surface-exposed on protein structures.
Lollier et al. (2011)