› › Structure analysis

Structure of tau peptide in complex with Tau5 antibody Fab fragment

X-ray diffraction
1.6Å resolution
PDB entry 4tqe coloured by chain, front view.
PDB entry 4tqe coloured by chain, side view.
PDB entry 4tqe coloured by chain, top view.
Source organisms:
Assembly composition:
hetero trimer (preferred)
Entry contents: 3 distinct polypeptide molecules

Quick links

Assemblies

Assembly 1 (preferred)
Download    3D Visualisation
Multimeric state: hetero trimer
Accessible surface area: 21159.6 Å2
Buried surface area: 6749.19 Å2
Dissociation area: 923.42 Å2
Dissociation energy (ΔGdiss): 6.61 kcal/mol
Dissociation entropy (TΔSdiss): 8.8 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-207557

Macromolecules

Ig-like domain-containing protein
Chain: L
Length: 218 amino acids
Theoretical weight: 24.1 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: A2NHM3 (Residues: 1-218; Coverage: 100%)
Gene names: Igk-C, Igkc
Pfam:
InterPro:
CATH: Immunoglobulins
Ig-like domain-containing protein in PDB entry 4tqe, assembly 1, front view.
Ig-like domain-containing protein in PDB entry 4tqe, assembly 1, side view.
Ig-like domain-containing protein in PDB entry 4tqe, assembly 1, top view.
Molecule details ›

Search similar proteins

Fab heavy chain
Chain: H
Length: 222 amino acids
Theoretical weight: 23.9 KDa
Source organism: Mus musculus
InterPro:
CATH: Immunoglobulins
Fab heavy chain in PDB entry 4tqe, assembly 1, front view.
Fab heavy chain in PDB entry 4tqe, assembly 1, side view.
Fab heavy chain in PDB entry 4tqe, assembly 1, top view.
Molecule details ›

Search similar proteins

Microtubule-associated protein tau
Chain: A
Length: 16 amino acids
Theoretical weight: 1.79 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P10636 (Residues: 532-547; Coverage: 2%)
Gene names: MAPT, MAPTL, MTBT1, TAU
Microtubule-associated protein tau in PDB entry 4tqe, assembly 1, front view.
Microtubule-associated protein tau in PDB entry 4tqe, assembly 1, side view.
Microtubule-associated protein tau in PDB entry 4tqe, assembly 1, top view.
Molecule details ›

Search similar proteins

Quick links