PDBe 4tq0

X-ray diffraction
2.7Å resolution

Crystal structure of human ATG5-ATG16N69

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Autophagy protein 5 Chains: A, C, E
Molecule details ›
Chains: A, C, E
Length: 289 amino acids
Theoretical weight: 34.04 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9H1Y0 (Residues: 1-275; Coverage: 100%)
Gene names: APG5L, ASP, ATG5
Sequence domains: Autophagy protein Apg5
Structure domains:
Autophagy-related protein 16-1 Chains: B, D, F
Molecule details ›
Chains: B, D, F
Length: 69 amino acids
Theoretical weight: 8.35 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q676U5 (Residues: 1-69; Coverage: 11%)
Gene names: APG16L, ATG16L1, UNQ9393/PRO34307

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PHOTON FACTORY BEAMLINE AR-NW12A
Spacegroup: P41212
Unit cell:
a: 93.094Å b: 93.094Å c: 245.577Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.207 0.203 0.274
Expression system: Escherichia coli BL21(DE3)