Structure analysis

Structure of the F249X mutant of Phosphatidylinositol-specific phospholipase C from Staphylococcus aureus

X-ray diffraction
2.5Å resolution
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

Assemblies

Assembly 1 (preferred)
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Multimeric state: monomeric
Accessible surface area: 12300 Å2
Buried surface area: 600 Å2
Dissociation area: 100 Å2
Dissociation energy (ΔGdiss): 1 kcal/mol
Dissociation entropy (TΔSdiss): 0 kcal/mol
Interface energy (ΔGint): 1 kcal/mol
Symmetry number: 1

Macromolecules

Chain: A
Length: 302 amino acids
Theoretical weight: 34.26 KDa
Source organism: Staphylococcus aureus subsp. aureus str. Newman
Expression system: Escherichia coli
UniProt:
  • Canonical: P45723 (Residues: 11-312; Coverage: 100%)
Gene names: NWMN_0041, plc
Pfam: Phosphatidylinositol-specific phospholipase C, X domain
InterPro:
CATH: Phosphatidylinositol (PI) phosphodiesterase

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