Structure analysis

Crystal structure of HA2-Del-L2seM, Central Coiled-Coil from Influenza Hemagglutinin HA2 without Heptad Repeat Stutter

X-ray diffraction
1.9Å resolution
Source organism: unidentified influenza virus
Assembly composition:
homo trimer (preferred)
Entry contents: 1 distinct polypeptide molecule

Assemblies

Assembly 1
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Multimeric state: homo trimer
Accessible surface area: 7100 Å2
Buried surface area: 3300 Å2
Dissociation area: 900 Å2
Dissociation energy (ΔGdiss): 13 kcal/mol
Dissociation entropy (TΔSdiss): 9 kcal/mol
Interface energy (ΔGint): -41 kcal/mol
Symmetry number: 1
Assembly 2 (preferred)
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Multimeric state: homo trimer
Accessible surface area: 7100 Å2
Buried surface area: 3400 Å2
Dissociation area: 900 Å2
Dissociation energy (ΔGdiss): 11 kcal/mol
Dissociation entropy (TΔSdiss): 9 kcal/mol
Interface energy (ΔGint): -39 kcal/mol
Symmetry number: 1

Macromolecules

Chains: A, B, C, D, E, F
Length: 38 amino acids
Theoretical weight: 4.71 KDa
Source organism: unidentified influenza virus
Expression system: Not provided
UniProt:
  • Canonical: A8TXX2 (Residues: 22-60; Coverage: 43%)
Gene name: HA

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