Function and Biology Details
Reactions catalysed:
ATP + acetyl-CoA + HCO(3)(-) = ADP + phosphate + malonyl-CoA
ATP + [biotin carboxyl-carrier protein]-biotin-N(6)-L-lysine + hydrogencarbonate- = ADP + phosphate + [biotin carboxyl-carrier protein]-carboxybiotin-N(6)-L-lysine
Biochemical function:
Biological process:
Cellular component:
- not assigned
Sequence domains:
- Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain
- Biotin carboxylation domain
- Biotin carboxylase, C-terminal
- ATP-grasp fold, subdomain 1
- Pre-ATP-grasp domain superfamily
- Biotin carboxylase-like, N-terminal domain
- ATP-grasp fold
- Acetyl-CoA carboxylase, biotin carboxylase
1 more domain
Structure analysis Details
Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Biotin carboxylase
Molecule details ›
Chain: A
Length: 468 amino acids
Theoretical weight: 51.35 KDa
Source organism: Haemophilus influenzae Rd KW20
Expression system: Escherichia coli
UniProt:
Sequence domains:
Length: 468 amino acids
Theoretical weight: 51.35 KDa
Source organism: Haemophilus influenzae Rd KW20
Expression system: Escherichia coli
UniProt:
- Canonical:
P43873 (Residues: 1-448; Coverage: 100%)
Sequence domains:
- Biotin carboxylase C-terminal domain
- Carbamoyl-phosphate synthase L chain, ATP binding domain
- Biotin carboxylase, N-terminal domain
