4rz0

X-ray diffraction
2.49Å resolution

Crystal Structure of Plasmodium falciparum putative histone methyltransferase PFL0690c

Released:
Source organism: Plasmodium (Laverania)
Entry authors: Jiang DQ, Tempel W, Loppnau P, Graslund S, He H, Ravichandran M, Seitova A, Arrowsmith CH, Edwards AM, Bountra C, Hui R, Hutchinson A, Lin YH, Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
SET domain-containing protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 146 amino acids
Theoretical weight: 16.78 KDa
Source organism: Plasmodium (Laverania)
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: W7FLI1 (Residues: 30-175; Coverage: 73%)
Gene name: PFAG_03779
Sequence domains: SET domain
Structure domains: SET domain

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P212121
Unit cell:
a: 48.73Å b: 53.474Å c: 111.592Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.222 0.22 0.275
Expression system: Spodoptera frugiperda