› 4rpo

X-ray diffraction
1.95Å resolution

PcpR inducer binding domain (Complex with 2,4,6-trichlorophenol)

Released:
DOI: 10.2210/pdb4rpo/pdb
PDB entry 4rpo coloured by chain, front view.
PDB entry 4rpo coloured by chain, side view.
PDB entry 4rpo coloured by chain, top view.
Source organism: Sphingobium chlorophenolicum
Primary publication:
Structures of the inducer-binding domain of pentachlorophenol-degrading gene regulator PcpR from Sphingobium chlorophenolicum.
Hayes RP, Moural TW, Lewis KM, Onofrei D, Xun L, Kang C
Int J Mol Sci 15 20736-52 (2014)
PMID: 25397598

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-156591 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
PCP degradation transcriptional activation protein Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 223 amino acids
Theoretical weight: 25.35 KDa
Source organism: Sphingobium chlorophenolicum
Expression system: Escherichia coli
UniProt:
  • Canonical: P52679 (Residues: 85-307; Coverage: 73%)
Gene name: pcpR
Sequence domains: LysR substrate binding domain
Structure domains: Periplasmic binding protein-like II

Ligands and Environments

3 bound ligands:
Ligand T6C 4 x T6C
Ligand GOL 2 x GOL
Ligand DMS 1 x DMS
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.2.1
Spacegroup: R3
Unit cell:
a: 169.751Å b: 169.751Å c: 110.115Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.178 0.178 0.209
Expression system: Escherichia coli

Quick links

Citations

1 review citation

CbbR, the Master Regulator for Microbial Carbon Dioxide Fixation.
Dangel et al. (2015)
7 other articles

3 mentions without citation

Transcription factor-based biosensors enlightened by the analyte.
Fernandez-López et al. (2015)
2 more