X-ray diffraction
1.4Å resolution

Crystal structure of the SAT domain from the non-reducing fungal polyketide synthase CazM with bound hexanoyl

Entry authors: Winter JM, Cascio D, Sawaya MR, Tang Y

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
SAT domain from CazM Chain: A
Molecule details ›
Chain: A
Length: 406 amino acids
Theoretical weight: 44.58 KDa
Source organism: Chaetomium globosum CBS 148.51
Expression system: Escherichia coli BL21(DE3)
  • Canonical: Q2GWK9 (Residues: 2-113, 114-125, 126-378; Coverage: 32%)
Gene name: CHGG_07645
Sequence domains: Starter unit:ACP transacylase in aflatoxin biosynthesis

Ligands and Environments

2 bound ligands:
1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-C
Spacegroup: P212121
Unit cell:
a: 45.67Å b: 52.36Å c: 168.03Å
α: 90° β: 90° γ: 90°
R R work R free
0.189 0.187 0.204
Expression system: Escherichia coli BL21(DE3)