Function and Biology

PaMorA dimeric phosphodiesterase. apo form

Source organism: Pseudomonas aeruginosa PAO1
Biochemical function: not assigned
Biological process: not assigned
Cellular component: not assigned

EC 3.1.4.52: Cyclic-guanylate-specific phosphodiesterase

Reaction catalysed:
Cyclic di-3',5'-guanylate + H(2)O = 5'-phosphoguanylyl(3'->5')guanosine
Systematic name:
Cyclic bis(3'->5')diguanylate 3-guanylylhydrolase
Alternative Name(s):
  • C-di-GMP phosphodiesterase
  • C-di-GMP-specific phosphodiesterase
  • Cyclic bis(3'->5')diguanylate phosphodiesterase
  • PDEA1
  • Phosphodiesterase
  • Phosphodiesterase A1
  • VieA

GO terms

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Sequence family

Pfam Protein family (Pfam)
PF00563
Domain description: EAL domain
Occurring in:
  1. Motility regulator
The deposited structure of PDB entry 4rni contains 2 copies of Pfam domain PF00563 (EAL domain) in Motility regulator. Showing 1 copy in chain B.

InterPro InterPro annotations
IPR001633
Domain description: EAL domain
Occurring in:
  1. Motility regulator
IPR035919
Domain description: EAL domain superfamily
Occurring in:
  1. Motility regulator

Structure domain

CATH CATH domain
3.20.20.450
Class: Alpha Beta
Architecture: Alpha-Beta Barrel
Topology: TIM Barrel
Homology: EAL domain
Occurring in:
  1. Motility regulator
The deposited structure of PDB entry 4rni contains 2 copies of CATH domain 3.20.20.450 (TIM Barrel) in Motility regulator. Showing 1 copy in chain B.