X-ray diffraction
1.76Å resolution

Crystal structure of LacI family transcriptional regulator CCPA from Weissella paramesenteroides, Target EFI-512926, with bound glucose

Entry authors: Patskovsky Y, Toro R, Bhosle R, Al Obaidi N, Chamala S, Attonito JD, Scott Glenn A, Chowdhury S, Lafleur J, Siedel RD, Hillerich B, Love J, Whalen KL, Gerlt JA, Almo SC, Enzyme Function Initiative (EFI)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
HTH lacI-type domain-containing protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 287 amino acids
Theoretical weight: 32.54 KDa
Source organism: Weissella paramesenteroides ATCC 33313
Expression system: Escherichia coli BL21(DE3)
  • Canonical: C5RBT0 (Residues: 53-337; Coverage: 85%)
Gene names: HMPREF0877_1426, ccpA
Sequence domains: Periplasmic binding protein-like domain
Structure domains: Rossmann fold

Ligands and Environments

1 bound ligand:
1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X29A
Spacegroup: P43212
Unit cell:
a: 102.564Å b: 102.564Å c: 128.055Å
α: 90° β: 90° γ: 90°
R R work R free
0.169 0.168 0.198
Expression system: Escherichia coli BL21(DE3)