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Serine Protease HtrA3, mutationally inactivated

X-ray diffraction
3.272Å resolution
PDB entry 4ri0 coloured by chain, front view.
PDB entry 4ri0 coloured by chain, side view.
PDB entry 4ri0 coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
homo trimer (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Serine protease HTRA3
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Multimeric state: homo trimer
Accessible surface area: 31708.69 Å2
Buried surface area: 5635.05 Å2
Dissociation area: 1,746.09 Å2
Dissociation energy (ΔGdiss): 12.92 kcal/mol
Dissociation entropy (TΔSdiss): 13.75 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-160670

Macromolecules

Serine protease HTRA3
Chains: A, B, C
Length: 332 amino acids
Theoretical weight: 36.31 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P83110 (Residues: 130-453; Coverage: 74%)
Gene names: HTRA3, PRSP
Pfam:
InterPro:
CATH:
Serine protease HTRA3 in PDB entry 4ri0, assembly 1, front view.
Serine protease HTRA3 in PDB entry 4ri0, assembly 1, side view.
Serine protease HTRA3 in PDB entry 4ri0, assembly 1, top view.
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