X-ray diffraction
2.3Å resolution

Apo crystal structure of CDPK4 from Plasmodium falciparum, PF3D7_0717500

Source organism: Plasmodium falciparum
Entry authors: Wernimont AK, Walker JR, Hutchinson A, Seitova A, He H, Loppnau P, Neculai M, Amani M, Lin YH, Ravichandran M, Arrowsmith CH, Edwards AM, Bountra C, Hui R, Lovato DV, Structural Genomics Consortium (SGC)

Function and Biology Details

Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Calcium-dependent protein kinase 4 Chain: A
Molecule details ›
Chain: A
Length: 520 amino acids
Theoretical weight: 60 KDa
Source organism: Plasmodium falciparum
Expression system: Spodoptera frugiperda
  • Canonical: Q8IBS5 (Residues: 10-528; Coverage: 98%)
Gene names: CDPK4, CPK4, PF3D7_0717500
Sequence domains: EF-hand domain pair
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P212121
Unit cell:
a: 70.654Å b: 75.548Å c: 92.562Å
α: 90° β: 90° γ: 90°
R R work R free
0.204 0.201 0.255
Expression system: Spodoptera frugiperda