4rg2

X-ray diffraction
1.5Å resolution

Tudor Domain of Tumor suppressor p53BP1 with small molecule ligand

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
TP53-binding protein 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 125 amino acids
Theoretical weight: 14.12 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q12888 (Residues: 1483-1606; Coverage: 6%)
Gene name: TP53BP1
Sequence domains: Tumour suppressor p53-binding protein-1 Tudor
Structure domains:

Ligands and Environments

3 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: C2221
Unit cell:
a: 73.548Å b: 100.458Å c: 83.348Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.198 0.197 0.22
Expression system: Escherichia coli BL21(DE3)