X-ray diffraction
2.15Å resolution

Structure of YTH-YTHDF2 in the free state


Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
YTH domain-containing family protein 2 Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 167 amino acids
Theoretical weight: 19.37 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: Q9Y5A9 (Residues: 408-552; Coverage: 25%)
Gene names: HGRG8, YTHDF2
Sequence domains: YT521-B-like domain
Structure domains: ph1033 like domains

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U
Spacegroup: P65
Unit cell:
a: 139.28Å b: 139.28Å c: 112.95Å
α: 90° β: 90° γ: 120°
R R work R free
0.216 0.213 0.27
Expression system: Escherichia coli