Structure analysis

Crystal structure of Ser/Thr kinase Pim1 in complex with Mitoxantrone derivatives

X-ray diffraction
2.651Å resolution
Source organism: Homo sapiens
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

Assemblies

Assembly 1 (preferred)
Download    3D Visualisation
Multimeric state: monomeric

Binding statistics and energies are not available for this assembly

Macromolecules

Chain: A
Length: 289 amino acids
Theoretical weight: 33.29 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P11309 (Residues: 29-313; Coverage: 91%)
Gene name: PIM1
Pfam: Protein kinase domain
InterPro:
CATH:

Search similar proteins