› 4r9p

X-ray diffraction
1.59Å resolution

An Expansion to the Smad MH2-family: The structure of the N-MH2 expanded domain

Released:
DOI: 10.2210/pdb4r9p/pdb
PDB entry 4r9p coloured by chain, front view.
PDB entry 4r9p coloured by chain, side view.
PDB entry 4r9p coloured by chain, top view.
Source organism: Drosophila melanogaster
Primary publication:
Structure of the N-terminal domain of the protein Expansion: an 'Expansion' to the Smad MH2
Beich-Frandsen M, Aragon E, Llimargas M, Benach J, Riera A, Pous J, Macias MJ
Acta Crystallogr. D Biol. Crystallogr. 71 844-853 (2015)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-106777 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
MH2 domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 242 amino acids
Theoretical weight: 28 KDa
Source organism: Drosophila melanogaster
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: A1Z8R1 (Residues: 1-240; Coverage: 23%)
Gene names: CG13188, Dmel\CG13188, Dmel_CG13188, Exp, exp
Sequence domains: MH2 domain
Structure domains: Tumour Suppressor Smad4

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALBA BEAMLINE XALOC
Spacegroup: P21
Unit cell:
a: 36.84Å b: 45.67Å c: 54.19Å
α: 90° β: 93.31° γ: 90°
R-values:
R R work R free
0.178 0.176 0.198
Expression system: Escherichia coli BL21(DE3)

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