X-ray diffraction
2.7Å resolution

Crystal structure of an active MCM hexamer


Function and Biology Details

Reaction catalysed:
ATP + H(2)O = ADP + phosphate
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo hexamer (preferred)
Entry contents:
1 distinct polypeptide molecule
DNA helicase; Minichromosome maintenance protein MCM Chains: A, B
Molecule details ›
Chains: A, B
Length: 613 amino acids
Theoretical weight: 69.47 KDa
Source organisms: Expression system: Escherichia coli
  • Canonical: Q9UXG1 (Residues: 2-269; Coverage: 39%)
  • Canonical: Q8U3I4 (Residues: 257-966; Coverage: 33%)
Gene names: MCM, PF0482, SSO0774
Sequence domains:
Structure domains:

Ligands and Environments

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-ID
Spacegroup: P63
Unit cell:
a: 118.902Å b: 118.902Å c: 199.317Å
α: 90° β: 90° γ: 120°
R R work R free
0.263 0.263 0.295
Expression system: Escherichia coli