4r7q

X-ray diffraction
1.98Å resolution

The structure of a sensor domain of a histidine kinase from Vibrio cholerae O1 biovar eltor str. N16961

Released:
Entry authors: Tan K, Zhou M, Kwon K, Anderson WF, Joachimiak A, Center for Structural Genomics of Infectious Diseases (CSGID)

Function and Biology Details

Reaction catalysed:
ATP + protein L-histidine = ADP + protein N-phospho-L-histidine
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Histidine kinase domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 222 amino acids
Theoretical weight: 25.07 KDa
Source organism: Vibrio cholerae O1 biovar El Tor str. N16961
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9KM24 (Residues: 38-256; Coverage: 47%)
Gene name: VC_A0565

Ligands and Environments

3 bound ligands:
1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P41212
Unit cell:
a: 88.6Å b: 88.6Å c: 106.993Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.185 0.184 0.203
Expression system: Escherichia coli BL21(DE3)