X-ray diffraction
2.55Å resolution

Plasmodium falciparum phosphoethanolamine methyltransferase D128A mutant in complex with S-adenosylhomocysteine and phosphoethanolamine


Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Methyltransferase type 11 domain-containing protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 258 amino acids
Theoretical weight: 30.11 KDa
Source organism: Plasmodium falciparum
Expression system: Escherichia coli BL21(DE3)
  • Canonical: Q6T755 (Residues: 9-266; Coverage: 97%)
Gene name: PMT
Sequence domains: Methyltransferase domain
Structure domains: Vaccinia Virus protein VP39

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P2
Unit cell:
a: 76.826Å b: 43.652Å c: 88.053Å
α: 90° β: 107.79° γ: 90°
R R work R free
0.205 0.203 0.258
Expression system: Escherichia coli BL21(DE3)