4r4l

X-ray diffraction
2.24Å resolution

Crystal structure of wt cGMP dependent protein kinase I alpha (PKGI alpha) leucine zipper

Released:

Function and Biology Details

Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
cGMP-dependent protein kinase 1 Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 49 amino acids
Theoretical weight: 5.88 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q13976 (Residues: 2-48; Coverage: 7%)
Gene names: PRKG1, PRKG1B, PRKGR1A, PRKGR1B
Structure domains: Single helix bin

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 5.0.1
Spacegroup: P6222
Unit cell:
a: 95.926Å b: 95.926Å c: 63.805Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.258 0.254 0.29
Expression system: Escherichia coli