Structure analysis

Structure and Function of Neisseria gonorrhoeae MtrF Illuminates a Class of Antimetabolite Efflux Pumps

X-ray diffraction
3.959Å resolution
Source organism: Neisseria gonorrhoeae FA19
Assembly composition:
homo dimer (preferred)
Entry contents: 1 distinct polypeptide molecule

Assemblies

Assembly 1 (preferred)
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Multimeric state: homo dimer
Accessible surface area: 43600 Å2
Buried surface area: 3600 Å2
Dissociation area: 1,800 Å2
Dissociation energy (ΔGdiss): 30 kcal/mol
Dissociation entropy (TΔSdiss): 15 kcal/mol
Interface energy (ΔGint): -42 kcal/mol
Symmetry number: 2

Macromolecules

Chains: A, B
Length: 522 amino acids
Theoretical weight: 56.17 KDa
Source organism: Neisseria gonorrhoeae FA19
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9RNX2 (Residues: 1-522; Coverage: 100%)
Gene names: WHOM_01006, WHOM_01392, abgT, mtrF
Pfam: AbgT putative transporter family
InterPro:

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