X-ray diffraction
1.98Å resolution

Crystal Structure of MTIP from Plasmodium falciparum in complex with a peptide-fragment chimera


Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
EF-hand domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 145 amino acids
Theoretical weight: 16.5 KDa
Source organism: Plasmodium falciparum 3D7
Expression system: Escherichia coli BL21(DE3)
  • Canonical: Q8I4W8 (Residues: 61-204; Coverage: 71%)
Gene name: PF3D7_1246400
Structure domains: EF-hand
Myosin-A Chain: B
Molecule details ›
Chain: B
Length: 15 amino acids
Theoretical weight: 1.74 KDa
Source organism: Plasmodium falciparum 3D7
Expression system: Not provided
  • Canonical: Q8IDR3 (Residues: 803-816; Coverage: 2%)
Gene names: MyoA, PF13_0233, PF3D7_1342600

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04-1
Spacegroup: P212121
Unit cell:
a: 36.71Å b: 55.76Å c: 75.86Å
α: 90° β: 90° γ: 90°
R R work R free
0.199 0.196 0.223
Expression systems:
  • Escherichia coli BL21(DE3)
  • Not provided