› 4quz

X-ray diffraction
2.35Å resolution

Crystal structure of Feline Norovirus P Domain

Released:
DOI: 10.2210/pdb4quz/pdb
PDB 4quz coloured by chain and viewed from the front.
PDB 4quz coloured by chain and viewed from the side.
PDB 4quz coloured by chain and viewed from the top.
Source organism: Norovirus cat/GIV.2/CU081210E/USA/2010
Primary publication:
Structural analysis of a feline norovirus protruding domain.
Singh BK, Glatt S, Ferrer JL, Koromyslova AD, Leuthold MM, Dunder J, Hansman GS
Virology 474 181-5 (2015)
PMID: 25463616

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
VP1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 341 amino acids
Theoretical weight: 36.66 KDa
Source organism: Norovirus cat/GIV.2/CU081210E/USA/2010
Expression system: Escherichia coli
UniProt:
  • Canonical: H8YRY9 (Residues: 225-565; Coverage: 59%)
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand EDO 5 x EDO
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE BM30A
Spacegroup: P21
Unit cell:
a: 57.74Å b: 99.92Å c: 59.61Å
α: 90° β: 97.92° γ: 90°
R-values:
R R work R free
0.217 0.214 0.268
Expression system: Escherichia coli

Quick links

Citations

1 review citation

Emergence of norovirus strains: A tale of two genes.
Parra GI. (2019)
3 other articles

1 mention without citation

Genomics Analyses of GIV and GVI Noroviruses Reveal the Distinct Clustering of Human and Animal Viruses.
Ford-Siltz et al. (2019)