› › Structure analysis

Crystal Structure of RON Sema-PSI-IPT1 extracellular domains in complex with MSP beta-chain

X-ray diffraction
3Å resolution
PDB 4qt8 coloured by chain and viewed from the front.
PDB 4qt8 coloured by chain and viewed from the side.
PDB 4qt8 coloured by chain and viewed from the top.
Source organism: Homo sapiens
Assembly composition:
Non-polymer only dimer (preferred)
Entry contents: 2 distinct polypeptide molecules

Quick links

Assemblies

Assembly 1
Download    3D Visualisation
Multimeric state: Non-polymer only dimer
Accessible surface area: 37300 Å2
Buried surface area: 2400 Å2
Dissociation area: 900 Å2
Dissociation energy (ΔGdiss): -6 kcal/mol
Dissociation entropy (TΔSdiss): 13 kcal/mol
Interface energy (ΔGint): 8 kcal/mol
Symmetry number: 1
Assembly 2 (preferred)
Download    3D Visualisation
Multimeric state: Non-polymer only dimer
Accessible surface area: 37000 Å2
Buried surface area: 2500 Å2
Dissociation area: 850 Å2
Dissociation energy (ΔGdiss): -6 kcal/mol
Dissociation entropy (TΔSdiss): 13 kcal/mol
Interface energy (ΔGint): 10 kcal/mol
Symmetry number: 1

Macromolecules

Macrophage-stimulating protein receptor beta chain
Chains: A, B
Length: 669 amino acids
Theoretical weight: 71.99 KDa
Source organism: Homo sapiens
Expression system: Drosophila melanogaster
UniProt:
  • Canonical: Q04912 (Residues: 25-683; Coverage: 48%)
  • Best match: Q04912-3 (Residues: 25-474)
Gene names: MST1R, PTK8, RON
Pfam:
InterPro:
CATH: YVTN repeat-like/Quinoprotein amine dehydrogenase
PDB 4qt8 contains 1 copy of Macrophage-stimulating protein receptor beta chain in assembly 2. This protein is highlighted and viewed from the front.
PDB 4qt8 contains 1 copy of Macrophage-stimulating protein receptor beta chain in assembly 2. This protein is highlighted and viewed from the side.
PDB 4qt8 contains 1 copy of Macrophage-stimulating protein receptor beta chain in assembly 2. This protein is highlighted and viewed from the top.
Molecule details ›

Search similar proteins

Hepatocyte growth factor-like protein beta chain
Chains: C, D
Length: 253 amino acids
Theoretical weight: 28.34 KDa
Source organism: Homo sapiens
Expression system: Drosophila melanogaster
UniProt:
  • Canonical: P26927 (Residues: 465-711; Coverage: 36%)
Gene names: D3F15S2, DNF15S2, HGFL, MST1
Pfam: Trypsin
InterPro:
CATH: Trypsin-like serine proteases
PDB 4qt8 contains 1 copy of Hepatocyte growth factor-like protein beta chain in assembly 2. This protein is highlighted and viewed from the front.
PDB 4qt8 contains 1 copy of Hepatocyte growth factor-like protein beta chain in assembly 2. This protein is highlighted and viewed from the side.
PDB 4qt8 contains 1 copy of Hepatocyte growth factor-like protein beta chain in assembly 2. This protein is highlighted and viewed from the top.
Molecule details ›

Search similar proteins

Quick links