› 4qs9

X-ray diffraction
2.1Å resolution

Arabidopsis Hexokinase 1 (AtHXK1) mutant S177A structure in glucose-bound form

Released:
DOI: 10.2210/pdb4qs9/pdb
PDB 4qs9 coloured by chain and viewed from the front.
PDB 4qs9 coloured by chain and viewed from the side.
PDB 4qs9 coloured by chain and viewed from the top.
Source organism: Arabidopsis thaliana
Primary publication:
Biochemical and structural study of Arabidopsis hexokinase 1.
Feng J, Zhao S, Chen X, Wang W, Dong W, Chen J, Shen JR, Liu L, Kuang T
Acta Crystallogr. D Biol. Crystallogr. 71 367-75 (2015)
PMID: 25664748

Function and Biology Details

Reaction catalysed: 
ATP + D-hexose = ADP + D-hexose 6-phosphate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Hexokinase-1 Chain: A
Molecule details ›
Chain: A
Length: 474 amino acids
Theoretical weight: 51.77 KDa
Source organism: Arabidopsis thaliana
Expression system: Escherichia coli
UniProt:
  • Canonical: Q42525 (Residues: 30-496; Coverage: 94%)
Gene names: At4g29130, F19B15.160, GIN2, HXK1
Sequence domains:
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand BGC 1 x BGC
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U
Spacegroup: P212121
Unit cell:
a: 44.781Å b: 93.128Å c: 101.797Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.2 0.198 0.235
Expression system: Escherichia coli

Quick links

Citations

4 review citations

Dynamic Nutrient Signaling Networks in Plants.
Li et al. (2021)
3 more