X-ray diffraction
1.75Å resolution

Crystal Structure of tudor domain of SMN1 in complex with a small organic molecule

Source organism: Homo sapiens
Entry authors: Liu Y, Tempel W, Iqbal A, Walker JR, Bountra C, Arrowsmith CH, Edwards AM, Brown PJ, Min J, Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Survival motor neuron protein Chain: A
Molecule details ›
Chain: A
Length: 67 amino acids
Theoretical weight: 7.41 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
  • Canonical: Q16637 (Residues: 82-147; Coverage: 22%)
Gene names: SMN, SMN1, SMN2, SMNC, SMNT
Structure domains: SH3 type barrels.

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: rigaku fr-e
Spacegroup: P65
Unit cell:
a: 27.789Å b: 27.789Å c: 112.817Å
α: 90° β: 90° γ: 120°
R R work R free
0.173 0.165 0.242
Expression system: Escherichia coli BL21(DE3)