› 4qq6

X-ray diffraction
1.75Å resolution

Crystal Structure of tudor domain of SMN1 in complex with a small organic molecule

Released:
DOI: 10.2210/pdb4qq6/pdb
PDB 4qq6 coloured by chain and viewed from the front.
PDB 4qq6 coloured by chain and viewed from the side.
PDB 4qq6 coloured by chain and viewed from the top.
Source organism: Homo sapiens
Entry authors: Liu Y, Tempel W, Iqbal A, Walker JR, Bountra C, Arrowsmith CH, Edwards AM, Brown PJ, Min J, Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Survival motor neuron protein Chain: A
Molecule details ›
Chain: A
Length: 67 amino acids
Theoretical weight: 7.41 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q16637 (Residues: 82-147; Coverage: 22%)
Gene names: SMN, SMN1, SMN2, SMNC, SMNT
Structure domains: SH3 type barrels.

Ligands and Environments

2 bound ligands:
Ligand UNX 3 x UNX
Ligand 36X 1 x 36X
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: rigaku fr-e
Spacegroup: P65
Unit cell:
a: 27.789Å b: 27.789Å c: 112.817Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.173 0.165 0.242
Expression system: Escherichia coli BL21(DE3)

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