Articles - 4qnz mentioned but not cited (1)
- Substrate binding and specificity of rhomboid intramembrane protease revealed by substrate-peptide complex structures. Zoll S, Stanchev S, Began J, Skerle J, Lepšík M, Peclinovská L, Majer P, Strisovsky K. EMBO J 33 2408-2421 (2014)
Reviews citing this publication (7)
- Understanding intramembrane proteolysis: from protein dynamics to reaction kinetics. Langosch D, Scharnagl C, Steiner H, Lemberg MK. Trends Biochem Sci 40 318-327 (2015)
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- Intramembrane proteases as drug targets. Verhelst SHL. FEBS J 284 1489-1502 (2017)
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- Rhomboid protease inhibitors: Emerging tools and future therapeutics. Strisovsky K. Semin Cell Dev Biol 60 52-62 (2016)
- Biophysical mechanism of rhomboid proteolysis: Setting a foundation for therapeutics. Bondar AN. Semin Cell Dev Biol 60 46-51 (2016)
- Substrate-Enzyme Interactions in Intramembrane Proteolysis: γ-Secretase as the Prototype. Liu X, Zhao J, Zhang Y, Ubarretxena-Belandia I, Forth S, Lieberman RL, Wang C. Front Mol Neurosci 13 65 (2020)
Articles citing this publication (39)
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- Rhomboid intramembrane protease YqgP licenses bacterial membrane protein quality control as adaptor of FtsH AAA protease. Began J, Cordier B, Březinová J, Delisle J, Hexnerová R, Srb P, Rampírová P, Kožíšek M, Baudet M, Couté Y, Galinier A, Veverka V, Doan T, Strisovsky K. EMBO J 39 e102935 (2020)
- Quantitative proteomics screen identifies a substrate repertoire of rhomboid protease RHBDL2 in human cells and implicates it in epithelial homeostasis. Johnson N, Březinová J, Stephens E, Burbridge E, Freeman M, Adrain C, Strisovsky K. Sci Rep 7 7283 (2017)
- Ten catalytic snapshots of rhomboid intramembrane proteolysis from gate opening to peptide release. Cho S, Baker RP, Ji M, Urban S. Nat Struct Mol Biol 26 910-918 (2019)
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- Derlin rhomboid pseudoproteases employ substrate engagement and lipid distortion to enable the retrotranslocation of ERAD membrane substrates. Nejatfard A, Wauer N, Bhaduri S, Conn A, Gourkanti S, Singh N, Kuo T, Kandel R, Amaro RE, Neal SE. Cell Rep 37 109840 (2021)
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- Sensitive Versatile Fluorogenic Transmembrane Peptide Substrates for Rhomboid Intramembrane Proteases. Tichá A, Stanchev S, Škerle J, Began J, Ingr M, Švehlová K, Polovinkin L, Růžička M, Bednárová L, Hadravová R, Poláchová E, Rampírová P, Březinová J, Kašička V, Majer P, Strisovsky K. J Biol Chem 292 2703-2713 (2017)
- Bacterial rhomboid proteases mediate quality control of orphan membrane proteins. Liu G, Beaton SE, Grieve AG, Evans R, Rogers M, Strisovsky K, Armstrong FA, Freeman M, Exley RM, Tang CM. EMBO J 39 e102922 (2020)
- Insights into the catalytic properties of the mitochondrial rhomboid protease PARL. Lysyk L, Brassard R, Arutyunova E, Siebert V, Jiang Z, Takyi E, Morrison M, Young HS, Lemberg MK, O'Donoghue AJ, Lemieux MJ. J Biol Chem 296 100383 (2021)
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- Embedded in the Membrane: How Lipids Confer Activity and Specificity to Intramembrane Proteases. Paschkowsky S, Oestereich F, Munter LM. J Membr Biol 251 369-378 (2018)
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- Involvement of a Membrane-Bound Amphiphilic Helix in Substrate Discrimination and Binding by an Escherichia coli S2P Peptidase RseP. Miyake T, Hizukuri Y, Akiyama Y. Front Microbiol 11 607381 (2020)
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- Probing catalytic rate enhancement during intramembrane proteolysis. Arutyunova E, Smithers CC, Corradi V, Espiritu AC, Young HS, Tieleman DP, Lemieux MJ. Biol Chem 397 907-919 (2016)
- The iRhom homology domain is indispensable for ADAM17-mediated TNFα and EGF receptor ligand release. Düsterhöft S, Kahveci-Türköz S, Wozniak J, Seifert A, Kasparek P, Ohm H, Liu S, Kopkanova J, Lokau J, Garbers C, Preisinger C, Sedlacek R, Freeman M, Ludwig A. Cell Mol Life Sci 78 5015-5040 (2021)
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- An automated protocol for modelling peptide substrates to proteases. Ochoa R, Magnitov M, Laskowski RA, Cossio P, Thornton JM. BMC Bioinformatics 21 586 (2020)
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- Mechanistic insights into intramembrane proteolysis by E. coli site-2 protease homolog RseP. Imaizumi Y, Takanuki K, Miyake T, Takemoto M, Hirata K, Hirose M, Oi R, Kobayashi T, Miyoshi K, Aruga R, Yokoyama T, Katagiri S, Matsuura H, Iwasaki K, Kato T, Kaneko MK, Kato Y, Tajiri M, Akashi S, Nureki O, Hizukuri Y, Akiyama Y, Nogi T. Sci Adv 8 eabp9011 (2022)
- Brucella abortus Encodes an Active Rhomboid Protease: Proteome Response after Rhomboid Gene Deletion. Marchesini MI, Poetsch A, Guidolín LS, Comerci DJ. Microorganisms 10 114 (2022)
- Electrospray ionization of native membrane proteins proceeds via a charge equilibration step. Yen HY, Abramsson ML, Agasid MT, Lama D, Gault J, Liko I, Kaldmäe M, Saluri M, Qureshi AA, Suades A, Drew D, Degiacomi MT, Marklund EG, Allison TM, Robinson CV, Landreh M. RSC Adv 12 9671-9680 (2022)
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- A combination of solid-state NMR and MD simulations reveals the binding mode of a rhomboid protease inhibitor. Bohg C, Öster C, Utesch T, Bischoff S, Lange S, Shi C, Sun H, Lange A. Chem Sci 12 12754-12762 (2021)
- Discovery and Biological Evaluation of Potent and Selective N-Methylene Saccharin-Derived Inhibitors for Rhomboid Intramembrane Proteases. Goel P, Jumpertz T, Mikles DC, Tichá A, Nguyen MTN, Verhelst S, Hubalek M, Johnson DC, Bachovchin DA, Ogorek I, Pietrzik CU, Strisovsky K, Schmidt B, Weggen S. Biochemistry 56 6713-6725 (2017)
- Rapid synthesis of internal peptidyl α-ketoamides by on resin oxidation for the construction of rhomboid protease inhibitors. Van Kersavond T, Konopatzki R, van der Plassche MAT, Yang J, Verhelst SHL. RSC Adv 11 4196-4199 (2021)
- Chemical Blockage of the Mitochondrial Rhomboid Protease PARL by Novel Ketoamide Inhibitors Reveals Its Role in PINK1/Parkin-Dependent Mitophagy. Poláchová E, Bach K, Heuten E, Stanchev S, Tichá A, Lampe P, Majer P, Langer T, Lemberg MK, Stříšovský K. J Med Chem 66 251-265 (2023)
- Enzyme-substrate hybrid β-sheet controls geometry and water access to the γ-secretase active site. Chen SY, Feilen LP, Chávez-Gutiérrez L, Steiner H, Zacharias M. Commun Biol 6 670 (2023)
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