4qnz

X-ray diffraction
2.55Å resolution

Crystal structure of rhomboid intramembrane protease GlpG F146I in complex with peptide derived inhibitor Ac-FATA-cmk

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Rhomboid protease GlpG Chain: A
Molecule details ›
Chain: A
Length: 200 amino acids
Theoretical weight: 22.7 KDa
Source organism: Escherichia coli str. K-12 substr. MC4100
Expression system: Escherichia coli
Structure domains: Rhomboid-like
ACE-PHE-ALA-THR-ALA-0QE Chain: B
Molecule details ›
Chain: B
Length: 6 amino acids
Theoretical weight: 467 Da
Source organism: Escherichia coli str. K-12 substr. MC4100
Expression system: Not provided

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID29
Spacegroup: P63
Unit cell:
a: 98.4Å b: 98.4Å c: 65.26Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.201 0.199 0.224
Expression systems:
  • Escherichia coli
  • Not provided