4qmj

X-ray diffraction
2.5Å resolution

The XMAP215 family drives microtubule polymerization using a structurally diverse TOG array

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cytoskeleton-associated protein 5 Chain: A
Molecule details ›
Chain: A
Length: 240 amino acids
Theoretical weight: 27.11 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q14008 (Residues: 846-1081; Coverage: 12%)
Gene names: CKAP5, KIAA0097
Sequence domains: CLASP N terminal
Structure domains: Leucine-rich Repeat Variant

Ligands and Environments

No bound ligands

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-ID
Spacegroup: P43212
Unit cell:
a: 79.125Å b: 79.125Å c: 68.499Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.215 0.208 0.276
Expression system: Escherichia coli