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Crystal structure of Aminopeptidase N in complex with the phosphinic dipeptide analogue LL-(R,S)-hPheP[CH2]Phe

X-ray diffraction
1.601Å resolution
PDB entry 4qme coloured by chain, front view.
PDB entry 4qme coloured by chain, side view.
PDB entry 4qme coloured by chain, top view.
Source organism: Neisseria meningitidis MC58
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Aminopeptidase N
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Multimeric state: monomeric
Accessible surface area: 33627.12 Å2
Buried surface area: 1835.61 Å2
Dissociation area: 0 Å2
Dissociation energy (ΔGdiss): 0 kcal/mol
Dissociation entropy (TΔSdiss): 0 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-191698

Macromolecules

Aminopeptidase N
Chain: A
Length: 866 amino acids
Theoretical weight: 98.51 KDa
Source organism: Neisseria meningitidis MC58
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9JYV4 (Residues: 2-867; Coverage: 100%)
Gene names: NMB1416, pepN
Pfam:
InterPro:
CATH:
Aminopeptidase N in PDB entry 4qme, assembly 1, front view.
Aminopeptidase N in PDB entry 4qme, assembly 1, side view.
Aminopeptidase N in PDB entry 4qme, assembly 1, top view.
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