4qkf

X-ray diffraction
1.99Å resolution

Crystal structure of human ALKBH7 in complex with N-oxalylglycine and Mn(II)

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Alpha-ketoglutarate-dependent dioxygenase alkB homolog 7, mitochondrial Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 200 amino acids
Theoretical weight: 22.58 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9BT30 (Residues: 17-215; Coverage: 90%)
Gene names: ABH7, ALKBH7, SPATA11, UNQ6002/PRO34564
Sequence domains: 2OG-Fe(II) oxygenase superfamily
Structure domains: Alpha-ketoglutarate-dependent dioxygenase AlkB-like

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BSRF BEAMLINE 3W1A
Spacegroup: P21
Unit cell:
a: 66.364Å b: 81.958Å c: 66.082Å
α: 90° β: 119.94° γ: 90°
R-values:
R R work R free
0.159 0.159 0.165
Expression system: Escherichia coli