PDBe 4qjl

X-ray diffraction
1.65Å resolution

Crystal structure of M. ulcerans phosphopantetheinyl transferase MuPPT


Function and Biology Details

Reaction catalysed:
CoA-(4'-phosphopantetheine) + apo-[acyl-carrier-protein] = adenosine 3',5'-bisphosphate + holo-[acyl-carrier-protein]
Biochemical function:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Phosphopantetheinyl transferase, PptII Chain: A
Molecule details ›
Chain: A
Length: 235 amino acids
Theoretical weight: 25.74 KDa
Source organism: Mycobacterium ulcerans Agy99
Expression system: Escherichia coli
  • Canonical: A0PQD8 (Residues: 1-227; Coverage: 100%)
Gene names: MUL_2141, pptII
Sequence domains:

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.2.1
Spacegroup: P212121
Unit cell:
a: 55.02Å b: 59.75Å c: 74.48Å
α: 90° β: 90° γ: 90°
R R work R free
0.162 0.16 0.208
Expression system: Escherichia coli