4qfh

X-ray diffraction
1.8Å resolution

Structure of a glucose-6-phosphate isomerase from Trypanosoma cruzi

Released:
Source organism: Trypanosoma cruzi
Entry author: Seattle Structural Genomics Center for Infectious Disease (SSGCID)

Function and Biology Details

Reaction catalysed:
Alpha-D-glucose 6-phosphate = beta-D-fructofuranose 6-phosphate
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Glucose-6-phosphate isomerase Chains: A, B
Molecule details ›
Chains: A, B
Length: 616 amino acids
Theoretical weight: 69.48 KDa
Source organism: Trypanosoma cruzi
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q4E5N1 (Residues: 1-608; Coverage: 100%)
Gene name: Tc00.1047053506529.508
Sequence domains: Phosphoglucose isomerase

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 21-ID-G
Spacegroup: P21
Unit cell:
a: 69.84Å b: 127.03Å c: 72.4Å
α: 90° β: 109.74° γ: 90°
R-values:
R R work R free
0.14 0.139 0.174
Expression system: Escherichia coli BL21(DE3)