PDBe 4q50

X-ray diffraction
3.07Å resolution

Function and Biology Details

Structure analysis Details

Assemblies composition:
homo dimer (preferred)
homo octamer
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Estrogen receptor Chains: A, B, C, D, E, F, G, H
Molecule details ›
Chains: A, B, C, D, E, F, G, H
Length: 260 amino acids
Theoretical weight: 29.61 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P03372 (Residues: 299-554; Coverage: 43%)
  • Best match: P03372-2 (Residues: 254-442)
Gene names: ESR, ESR1, NR3A1
Sequence domains: Ligand-binding domain of nuclear hormone receptor
Structure domains: Retinoid X Receptor

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-BM
Spacegroup: P212121
Unit cell:
a: 104.651Å b: 165.244Å c: 191.384Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.19 0.216 0.283
Expression system: Escherichia coli