Function and Biology Details
Reactions catalysed:
Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1)
Selective cleavage of Gln-|-Gly bond in the poliovirus polyprotein. In other picornavirus reactions Glu may be substituted for Gln, and Ser or Thr for Gly.
Selective cleavage of Tyr-|-Gly bond in picornavirus polyprotein.
NTP + H(2)O = NDP + phosphate
Biochemical function:
Biological process:
- not assigned
Cellular component:
Structure analysis Details
Assembly composition:
hetero 240-mer (preferred)
Assembly name:
Coxsackievirus capsid protein VP1 (preferred)
PDBe Complex ID:
PDB-CPX-197697 (preferred)
Entry contents:
4 distinct polypeptide molecules
Macromolecules (4 distinct):
Coxsackievirus capsid protein VP1
Molecule details ›
Chain: 1
Length: 305 amino acids
Theoretical weight: 34.38 KDa
Source organism: Coxsackievirus A24
UniProt:
Structure domains: Jelly Rolls
Length: 305 amino acids
Theoretical weight: 34.38 KDa
Source organism: Coxsackievirus A24
UniProt:
- Canonical:
V9VEF3 (Residues: 581-885; Coverage: 14%)
Structure domains: Jelly Rolls
Coxsackievirus capsid protein VP2
Molecule details ›
Chain: 2
Length: 271 amino acids
Theoretical weight: 29.82 KDa
Source organism: Coxsackievirus A24
UniProt:
Structure domains: Jelly Rolls
Length: 271 amino acids
Theoretical weight: 29.82 KDa
Source organism: Coxsackievirus A24
UniProt:
- Canonical: V9VEF3 (Residues: 70-340; Coverage: 12%)
Structure domains: Jelly Rolls
Coxsackievirus capsid protein VP3
Molecule details ›
Chain: 3
Length: 240 amino acids
Theoretical weight: 26.64 KDa
Source organism: Coxsackievirus A24
UniProt:
Structure domains: Jelly Rolls
Length: 240 amino acids
Theoretical weight: 26.64 KDa
Source organism: Coxsackievirus A24
UniProt:
- Canonical: V9VEF3 (Residues: 341-580; Coverage: 11%)
Structure domains: Jelly Rolls
Coxsackievirus capsid protein VP4
Molecule details ›
Chain: 4
Length: 69 amino acids
Theoretical weight: 7.32 KDa
Source organism: Coxsackievirus A24
UniProt:
Structure domains: Picornavirus coat protein VP4
Length: 69 amino acids
Theoretical weight: 7.32 KDa
Source organism: Coxsackievirus A24
UniProt:
- Canonical: V9VEF3 (Residues: 1-69; Coverage: 3%)
Structure domains: Picornavirus coat protein VP4
