X-ray diffraction
1.44Å resolution

The crystal structure of NHERF1 PDZ2 CXCR2 complex revealed by the NHERF1 CXCR2 chimeric protein


Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Na(+)/H(+) exchange regulatory cofactor NHE-RF1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 92 amino acids
Theoretical weight: 9.92 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: O14745 (Residues: 150-235; Coverage: 24%)
Gene names: NHERF, NHERF1, SLC9A3R1
Sequence domains: PDZ domain
Structure domains: Pdz3 Domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 21-ID-F
Spacegroup: P21
Unit cell:
a: 32.751Å b: 55.349Å c: 45.226Å
α: 90° β: 90.74° γ: 90°
R R work R free
0.167 0.165 0.195
Expression system: Escherichia coli